Systems biology is an approach in biomedical research to understanding the larger picture—be it at the level of the organism, tissue, or cell—by putting its pieces together. It's in stark contrast to decades of reductionist biology, which involves taking the pieces apart.

Metagenomics is a molecular tool used to study DNA taken from environmental samples. This lets you mathematically infer microorganisms present, without the necessity of obtaining pure cultures.

This would be like saying, “Based on the species which are common to temperature forests, we can predict that there are probably deer in the region.”

Metabolomics: the scientific study of the set of metabolites present within an organism, cell, or tissue.

This is like saying, “See that deer scat? There is evidence that there are deer around here.”

Another way to think of it is that metagenomics may tell you a virus or specific pathogen is likely to be in the area, however, we can’t tell how active it is or how its influencing the overall environment. Metabolomics allows us to examine the excreted metabolites to see the impact on the environment as a whole.

Its these metabolites (waste products) which affect the larger growing region and metabolism. As they swim in the electric matrix releasing their own gases, they influence the temperature and moisture levels of surrounding tissue. They also affect the electrical activity in the region.

This effects extracellular electrical activity. This electricity guides and signals the polarity of gut epithelial cells causing holding or leaking in the gut. They do this through the sodium potassium pumps which actively transport water and electrolytes and help to maintain fluid homeostasis.

Because of this we can examine the body holistically looking at traditional signs and symptoms as well as electrical activity, metabolites, and pressure levels within the an area to get a sense for its overall diagnostic pattern.

This is where science and tradition meet and advance together toward the future of medicine.

This is crucial because we are not only what we eat, we are truly products of our environments.

Bacteria, archaea, fungi, viruses loan us genes they have for cross methylation. They influence how our DNA is flipped on or off.